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Top 10 Online Prescription Skincare Brands in North America

With the rising demand for customized or personalized skincare products, online prescription skincare is an emerging trend in the skincare industry.
However, the growing market isn’t the only aspect behind this custom skincare product trend.
The thing is, many dermatologists across the globe consider prescription skincare products as a “drug”.
Why? Well, it is designed as per the skin condition of the people.
Furthermore, the products must be approved by the FDA before it becomes available to the public.
As a result, people are preferring prescription skincare products for their various skin concerns such as
  • Acne
  • Sun damage
  • Dark spots
  • Rosacea
Now the question is, how to select the right online prescription skin care services?
Don’t worry, you are in the right place.
To help you choose the right prescription skincare solutions, we are here listing the top online prescription skincare brands in North America.

Top 10 Online Prescription Skincare Brands in North America

1: Nurx

Ratings: 4.2 stars with over 6.7k ratings

Average pricing: Starting from $25/month



Nurx app is one of the most affordable and convenient online skincare solution providers in North America.

As an online prescription skincare brand, it offers several skincare solutions for acne, anti-aging, and rosacea.

How does it work?

  • Share your skincare history and images
  • A certified dermatologist will review your skin condition
  • A dermatologist will prescribe you a personalized skincare treatment
  • Medication delivery at your doorstep
  • A follow-up visit to monitor your skincare treatment progress

2: Hers

Ratings: 4.7 stars with over 1.5k ratings

Average pricing: Starting from $24/month


Hers is not only delivering prescription skincare solutions but also provides non-prescription skincare and telehealth services with the help of certified dermatologists.

In addition to this, it offers numerous skincare products in its online store, including hair loss products.


  • Acne cream
  • Anti-aging cream
  • Dark spot corrector
  • Sunscreen
  • Water cleanser
  • Supplements
  • Hydro bounce moisturizer


  • Custom and personalized prescription
  • At-home delivery
  • Dermatologist-trusted skincare products
  • Quality care experience with telehealth services

3: Felix Health

Ratings: 3.9 star (As per the Trustpilot)

Average pricing: Online visits cost $40

Felix Health

Felix Health is known for its fast, convenient, and easily accessible online prescription skincare services in Canada.

As a top-rated prescription skincare brand, Felix Health offers telehealth and free prescription delivery at the same time for acne, allergies, hair loss, and many more.

How does it work?

  • Conduct an online visit with a qualified dermatologist
  • Get your skincare prescription
  • Free delivery at your doorstep


  • Choose a refill schedule as per your needs
  • For any query, you can communicate with an online pharmacist
  • High-qualified dermatologists
  • Free prescription delivery

4: Ro:

Ratings: 4.9 stars with over 1.2k ratings

Average pricing:

For custom Rx treatment, it costs $9 in the first month. After that, you need to pay $58 for each new order.

And for a custom Rx system, you will be charged $21 in the first month. After that, you need to pay $82 for each order.


Ro is a direct-to-patient skincare solutions provider in North America.

As an online prescription skincare brand, Ro offers personalized and custom skincare products as per your skincare goals.

Its custom Rx treatment includes science-baked ingredients such as:

  • Tretinoin
  • Azelaic acid
  • Niacinamide
  • Vitamin E acetate
  • Magnesium ascorbyl phosphate
  • Tranexamic acid
  • Ceramides
  • Hyaluronic acid

With that, Ro provides custom Rx treatment for:

  • Acne
  • Clogged pores
  • Dark spots
  • Uneven skin tone
  • Fine lines
  • Wrinkles
  • Skin firmness
  • Skin texture
  • Inflammation
  • Redness
  • Dryness
  • Dullness


  • Free and unlimited check-ins
  • US-licensed healthcare professionals
  • Award-winning custom Rx treatment

5: Musely

Ratings: 4.8 stars with over 5.6k ratings

Average pricing: Starting from $20


Musely is one of the leading online prescription skincare solution providers in the USA.

With highly-qualified dermatologists and pharmacists, Musely offers skin care services by using the most effective therapeutic and medication approaches.

As a result, it has 300,000+ real patients across North America.

Musely offers prescription skincare solutions for:

  • Acne
  • Dark spots
  • Anti-aging
  • Rosacea
  • Hair loss


  • No doctor’s office visit
  • Free home delivery
  • Customized formulas
  • Freshly compounded
  • More affordable

6: Curology

Ratings: 5-star reviews by 9k+ customers

Curology ratings

Pricing: Custom skincare treatment starts from $29.95/month


Curology offers custom-formulated skincare solutions as per the customers’ skin goals and needs.

Using Curology online prescription skincare platform, customers can simply upload their skin images or can track their skincare progress without any complexity.

With an experienced and committed dermatologists team, Curology mainly focuses on acne and anti-aging skincare solutions.


  • Cleanser
  • Moisturizer
  • Acne body wash
  • Emergency spot patches
  • Sunscreens
  • Lip balm
  • Makeup remover

7: Apostrophe

Ratings: 4.7 out of 5 based on 9k+ reviews

Average pricing: Online consultation starts from $20/visit


As a leading online prescription skincare brand, Apostrophe’s primary focus is to deliver the most effective and comprehensive treatment for acne skin conditions.

Apart from that, it offers several skincare solutions such as

  • Redness
  • Skincare texture
  • Dark spots
  • Breakouts

In addition to this, Apostrophe has a certified dermatologist that offers both topical and oral skincare medication.


  • Easiest virtual visit with a dermatologist
  • You can upload selfies of your skin
  • Both topical and oral medication
  • Personalized and long-term treatment for hormonal acne

8: Maple

Ratings: 4.8 stars based on 21.7k reviews

Average pricing: Online consultation starts at $49 per visit and $30/month for the membership.


Maple is a Canada-based online skincare solution provider.

With Canadian-licensed dermatologists, Maple not only offers prescription skincare but also provides virtual care services and skincare advice.

Using the app, patients can directly communicate with the dermatologist within 34 hours from mobile, tablet, or computer.

Skincare solutions:

  • Eczema
  • Acne
  • Rash
  • Fungal infection
  • Hair loss


  • Digital prescription via SMS or email
  • Free prescription delivery
  • Fast and secure access to your skincare records

9: First Derm

Ratings: Best online medical app in 2021 with 4.2 stars out of 5

Average pricing: Online dermatologist solutions start from $34.95/visit

First Dirm

First Derm is one of the best online dermatologist solution providers in North America with over 400,000+ users.

With board-certified dermatologists and research-backed skincare solutions, First Derm offers online skin care services for over 25+ skin-related conditions.

How does it work?

  • Open the app
  • Click your skin condition image
  • Upload it on the app
  • A board-certified dermatologist will contact you within 24 hours
  • Ideal skincare treatment with online prescription services

In addition to this, First Derm also guides users on their several skins and allergy-related concerns via the mobile app.

10: SkyMD

Ratings: 4.8 out of 5 based on 1.9k reviews

Average pricing: Depends on your insurance plans


SkyMD is the leading dermatologist solutions provider in the USA.

It offers fast, convenient, and easily accessible telehealth and online prescription skincare with a board-certified dermatologist.

In addition to this, SkyMD offers dermatologist services for over 15+ skin-related diseases or conditions.


  • Conduct virtual meetings within 24 hours
  • Fast and affordable solution
  • Prescription order supports at 500+ pharmacies
  • Online prescription and refills

Are you planning to start something similar? Know how we can help you

We are an Ontario-based healthcare IT company.
As a healthcare IT company, we have been investing 8 hours a day for over 8+ years only for the betterment of patients and providers.
As a result, we have earned ultimate expertise and understanding of healthcare IT.
With that, we can help you with mobile apps, web apps, business strategies, and compliance needs for your online prescription skincare services.
To do so, we have an experienced and dedicated team of healthcare professionals, UI/UX designers, web and app developers, business analysts, compliance specialists, and QA engineers.
For us, knowledge without actions is meaningless and that’s the reason we always deliver more than our client’s expectations.